Stars: Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood, Bill Murray, Molly Shannon

Director: Peter Farrelly

Summary: Frank catches a cold and the inside of his body, known as the 'The City Of Frank' is the venue of a fight between the white blood cell cop, Drixorial and the invading viruses.

With OSMOSIS JONES, triple threat writer-director-producer brothers Bobby and Peter Farrelly (THERE'S SOMETHING ABOUT MARY) successfully move into the live-action/animation genre. Frank (Bill Murray), a scruffy, overweight zoo keeper, revels in his unhealthy habits much to the chagrin of his young daughter, Shane (Elena Franklin). When Frank eats a dirty hard-boiled egg, the contagion-filled food enters The City of Frank, under the jurisdiction of germ-fighting white blood cell, Osmosis Jones (voiced by Chris Rock). A renegade cop in desperate need of a good case, Jones teams up with Drix (voiced by David Hyde Pierce), a superhero cold pill sent in to fight Frank's sore throat. The duo soon discovers that the troublesome egg carried a particularly evil germ, Thrax (voiced by Laurence Fishburne), who makes dastardly plans while hiding behind seemingly harmless cold symptoms. Jones and Drix struggle to convince Mayor Phlegmming (voiced by William Shatner) and his pretty aide, Leah (voiced by Brandy Norwood) of the danger, and to find the silky speaker, Red Death, before he does Frank true harm. Full of inventive sight gags and typical Farrelly gross-out humor, OSMOSIS JONES is a funny, clever blend of buddy cop romp, cartoon sci-fi, and fable, for both kids and adults.

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After the stiff attempts at realism in many recent features, it's a treat to see broad cartoon-style animation on the big screen in Osmosis Jones, a spoof of cop movies set inside the human body. The title character (voice by Chris Rock) is a street-smart white blood cell, working for Frank's immune system. He and Drix (David Hyde Pierce), an over-the-counter cold capsule, are reluctant partners fighting what appears to be a minor infection. Osmosis discovers Frank has really contracted a fatal virus, Thrax (Laurence Fishburne): he battles a corrupt body politic led by a venal mayor (William Shatner) to save Frank's life and win the affection of the mayor's aide, Leah (Brandy Norwood). Rock's motor-mouth delivery can get annoying, but it contrasts nicely with straight arrow Drix (imagine a fussy Buzz Lightyear). Excellent drawing and a powerful vocal performance make Thrax a genuinely frightening villain.

Osmosis Jones is about two-thirds animation and one-third live action, which is why two-thirds of the film is entertaining and funny, and one-third is not. The life Osmosis and Drix save belongs to Frank, a slob played in live-action sequences by Bill Murray, who's undercut rather than supported by Chris Elliott and Molly Shannon. Shamelessly over-the-top performances make the human characters seem flatter than the two-dimensional cartoons. The live action was shot by the Farrelly brothers and features lots of gross-out gags about zits, flatulence, vomit, etc. The audience endures these leaden segments, waiting to get back to the animation--and the real comedy. Suitable for ages 9 and up: profanity, violence, bodily function jokes. --Charles Solomon, Amazon.com

Aspect Ratio:	2.35 Wide Screen
Main Language:	English
Region:	Region 2
Special Features:	Audio Commentary, Two Documentaries, Interactive Adventure, Deleted Spleens, Interactive Menus, Scene Access, Trailer
Subtitles:	Danish, Dutch, English, Finnish, French, German, Greek, Hebrew, Icelandic, Norwegian, Portuguese, Spanish, Swedish, Turkish
Year:	2001
Release Date:	March 18, 2002
Runtime:	95 minutes
Certification:
Catalogue Number:	D 021323
Keywords:	Animated, Action, Jones, Live, Comedy, General, Wide, Screen, Osmosis
Genre:	Comedy